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Maternal Diet in Third Trimester Linked to Infant Mental Health Risks, Study Finds

02/04/2025
in News
Maternal Diet in Third Trimester Linked to Infant Mental Health Risks, Study Finds

A recent study published in Scientific Reports reveals that a mother’s diet during the third trimester of pregnancy may significantly influence the mental health of her child. The research highlights a potential link between maternal nutrition and infant temperament and behavioral development.

Study Overview

The study focused on examining how maternal diet during both the second and third trimesters impacts the mental and behavioral health of infants. The results showed that foods that cause rapid spikes in blood sugar levels during pregnancy could affect the infant’s temperament and behavioral patterns.

“These findings offer opportunities to improve nutrition during pregnancy, which may lead to better outcomes for infant behavioral health by focusing on specific dietary changes and timing,” said Dr. Elizabeth Wood, the lead author and assistant professor of psychiatry at OHSU School of Medicine.

Research Objectives and Methodology

The research aimed to assess how prenatal maternal diet, glycemic index (GI), body fat, and insulin resistance affect the emotional regulation of infants, particularly negative emotions. The study drew data from a long-term analysis of how perinatal nutrition influences neurodevelopment in infants.

Data was collected through participant-reported dietary intake, body composition assessments, and blood samples taken during the second and third trimesters. Infant behavior and emotional regulation were observed through questionnaires filled out by caregivers when the child was six months old.

Study Population and Measurements

The study included pregnancies from 2018 to 2021, with mothers reporting their diet through six unannounced recalls during the second and third trimesters. The glycemic index for the foods consumed was calculated using specialized research software. Body fat levels were measured using a body composition tracking system, and fasting blood samples were taken to assess glucose and insulin levels.

Other data points included maternal age, race, prenatal stress, socioeconomic status, and other factors that might influence maternal health and diet.

Key Findings

The study found that women with gestational diabetes had significantly higher levels of body fat, dietary GI, and insulin resistance compared to those without the condition. Additionally, these factors were higher in women using synthetic insulin.

A notable association was observed between insulin resistance in the second trimester and infant negative emotions (NA) at six months, particularly fear. Furthermore, a higher third-trimester dietary GI was linked to increased sadness in infants, as reported by their caregivers.

While no significant associations were found between second-trimester body fat and infant NA, third-trimester GI had the most noticeable impact on infant emotional regulation, including sadness.

Implications for Maternal Nutrition

The study indicates that maternal dietary quality, especially during the third trimester, plays a crucial role in shaping infant neurodevelopment. While third-trimester body fat and insulin resistance were not significantly associated with infant NA, the dietary GI emerged as the most influential factor in determining infant emotional health.

The researchers suggest that dietary interventions aimed at reducing high-GI foods could help improve infant neurodevelopmental outcomes, providing a simple, practical way to support better mental health in children.

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